Selected Publications
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Regulation of the collagenase activity of cathepsins by glycosaminoglycans.
Li, Z., Yasuda, Y., Li, W. Bogyo, M., Katz, N., Gorden, R. Fields, G.B., Brömme, D.
J. Biol.Chem. 279, 5470-5479, 2004.
Cysteine protease cathepsin F is present in atherosclerotic lesions and induces low density lipoprotein aggregation, fusion, and retention to human aortic proteoglycans in vitro.
Öörni, K., Sneck, M., Brömme, D., Pentikäinen, M.O., Mäyränpää, M., Aitio, H., Kovanen, P.T.
J.Biol. Chem. 259, 34776-84, 2004.
Cathepsin V: A novel and potent elastolytic activity expressed in activated macrophages.
Yasuda, Y., Li, Z., Greenbaum. D., Bogyo, M., Weber, E., Brömme, D.
J. Biol. Chem. 279, 36761-70, 2004.
Comparative substrate specificity analysis of recombinant human cathepsin V and cathepsin L. Arch.
Puzer, L., Cotrin, S.S., Alves, M.F., Egborge, T., Araujo, M.S., Juliano, M.A., Juliano, L., Brömme, D., Carmona, A.K.
Biochem. Biophys. 430, 274-83, 2004.
Cathepsin V. Cathepsin V is involved in the Degradation of Invariant Chain in Human Thymus and is Overexpressed in Myasthenia Gravis.
Tolosa, E., Li, W., Yasuda, Y., Denzin, L.K., Stevanovic, S., Driessen, C., Kurek, R., Weber, E., Melms, A., Brömme, D.
J. Clin. Invest. 2003;112:517-526, 2003.
Selective Inhibition of the Collagenolytic Activity of Human Cathepsin K by Altering its S2 Subsite Specificity.
Lecaille, F., Choe, Y., Brandt, W., Li, Z., Charles, S., Craik, C.S., Brömme, D.
Biochemistry 41, 8447-8454, 2002.
Collagenase activity of cathepsin K requires chondroitin sulfate.
Li, Z., Hou, W.S., Escalante, C., Gelb, B.D., Brömme, D.
J. Biol. Chem. 277, 28669-28676, 2002.
Comparison of cathepsins K and S expression within the rheumatoid and osteoarthritic synovium.
Hou WS, Li W, Keyszer, G., Weber, E., Levy, R., Klein, M.J., Gravallese, E.M, Goldring, S.R., Brömme, D.
Arthritis & Rheumatism 46, 663-674, 2002.
Human and Parasitic Papain-like Cysteine Proteases: Their Role in Physiology and Pathology. Lecaille, F., Kaleta, J., Brömme, D.
Chem Rev 102, 4459-4488, 2002.
