Strynadka Lab Publications

Selected Publications

Molecular structure of the acyl-enzyme intermediate in beta-lactam hydrolysis at 1.7 A resolution.
N.C. Strynadka, H. Adachi, S.E. Jensen, K. Johns, A. Sielecki, and M.N. James
Nature 359(6397), 700-5 (1992)

Structural and kinetic characterization of a beta-lactamase-inhibitor protein.
N.C. Strynadka, S.E. Jensen, K. Johns, H. Blanchard, A. Matagne, J.M. Frere, and M. James
Nature 368(6472), 657-60 (1994)

A potent new mode of beta-lactamase inhibition revealed by the TEM-1/BLIP complex at 1.7 A resolution.
N.C. Strynadka, S.E. Jensen, P.M. Alzari and M.N. James
Nature: Structural Biology 3, 252-261 (1996)

Current molecular docking programs successfully predict a large protein-protein complex.
N.C. Strynadka, M. Eisensten, B. Shoichet, T. Kunts, R. Duncan, A. Olson, R. Abagyan, M. Totrov, R. Jackson, M. Sternberg, J. Cherfils, J. Janin and M.N. James
Nature: Structural Biology 3, 233-239 (1996)

Structure-based design of a potent transition state analog for TEM-1 Beta Lactamase: X-ray crystallographic analysis at 1.7 A resolution.
N.C. Strynadka, R. Martin, S.E. Jensen and B. Jones
Nature: Structural Biology 3, 688-699 (1996)

Crystal structure of a bacterial signal peptidase in complex with a beta-lactam inhibitor.
M. Paetzel, R.E. Dalbey and N.C. Strynadka
Nature 396, 186-90 (1998)

Crystal structure of enteropathogenic Escherichia coli intimin-receptor complex.
Y. Luo, E.A. Frey, R. Pfuetzner, L. Craigh, D. Knoechel, C. Haynes, B.B. Finlay and N.C. Strynadka
Nature 405, 1073-1077 (2000)

Crystal structure of the class D beta-lactamase OXA-10.
M. Paetzel, F. Danel, L. De Castro, S. Mosimann, G.P. Malcolm Page, and N.C. Strynadka
Nature: Structural Biology 7, 918-925 (2000)

Crystal structure of the retaining galactosyltransferase LgtC from Neisseria mentingitidis in complex with donor and acceptor sugar analogs.
K. Persson, H.D. Ly, M. Dieckelmann, W. Wakarchuk, S.G. Withers, and N.C. Strynadka
Nature: Structural Biology 8, 166-175 (2001)

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